Mechanisms of lipoplex formation: dependence of biological properties of transfection complexes on formulation
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چکیده
decreased to 2276±288 nm at the end of 120 min having a polydispersity over 0.7 for both of the incubations. Among the CLDC10 and CLDC11 prepared at the highest ratios (1:0.186 w/w) the complexation process was the fastest and the size observed between 2900 nm to 3044 nm remained nearly unchanged with CLDC10, whereas a progressive increase and then decrease was observed with CLDC11. The measured size of CLDC10 was 2412±62.7 nm at the end of 120 min, however the polydispersity index was over 0.7. The complexation was completed at all incubation periods for both complexes as confirmed by the gel electrophoresis analysis.
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